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16004

Total database: 17430
Struktur (SMILES)
12010 (75.0%)
Target
9041 (56.5%)
Genomik
112 (0.7%)
Referensi
16004 (100.0%)

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Hasil Pencarian (16004)

Halaman 113 / 321
CSIC002 DB18584
small molecule

CSIC002 is a small-molecule Sema-3A inhibitor. It is being investigated for the treatment of anterior ischemic optic neuropathy.

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CSL-689 DB17726
biotech

CSL689 is a recombinant fusion protein linking coagulation factor VIIa with albumin (rVIIa-FP).

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CSL324 DB16359
biotech

CSL324 is a fully human anti-G-CSFR antibody shown to have the ability to control G-CSF-mediated neutrophilia in cynomolgus macaques.[A225626] It has potential applications in various inflammatory conditions such as cystic fibrosis, inflammatory bowel disease…

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CT-001 DB18284
biotech

Deskripsi belum tersedia.

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CT-011 DB05916
biotech

CT-011 is a humanized monoclonal antibody directed against a B7 family-associated protein, in patients with advanced haematological malignancies. It is directed against human PD-1 (programmed cell death 1; PDCD1), with immunomodulating and antitumor activitie…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntineoplastic Agents +7
Target Protein:
Programmed cell death protein 1
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CT-179 DB17114
small molecule | CAS: 1996636-69-1

Deskripsi belum tersedia.

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CT-2584 DB13098
small molecule | CAS: 166981-13-1

CT-2584 has been used in trials studying the treatment of Prostate Cancer.

Kategori:
AlkaloidsHeterocyclic Compounds, Fused-RingPhospholipase D, antagonists & inhibitors +2
Target Protein:
Choline-phosphate cytidylyltransferase B
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CT041 DB18288
biotech

CT041 is an autologous CAR T-cell product candidate against protein Claudin18.2 (CLDN18.2).

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CT103A DB18180
biotech

CT103A is an investigational BCMA-targeted genetically modified autologous T-cell immunotherapy.

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CT120 DB18181
biotech

CT120 is an investigational autologous CD19/22 targeted CAR-T cell immunotherapy.

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CTA018 DB05024
small molecule

CTA018 is a member of a new class of vitamin D analogues with a dual mechanism of action, called Vitamin D Signal Amplifiers. This proprietary new drug is both a potent inhibitor of CYP24 (the enzyme responsible for the breakdown of vitamin D) and a potent ac…

Target Protein:
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialVitamin D3 receptor
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CTB001 DB18316
biotech

CTB001 is an anti-claudin 18.2 autologous chimeric antigen receptor (CAR) T-cell therapy under investigation for the treatment of gastric cancers.[L48146]

Kategori:
Amino Acids, Peptides, and ProteinsAnticoagulantsAntithrombin Proteins +8
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CTCE-0214 DB05934
small molecule | CAS: 577782-52-6

CTCE-0214 is a stable peptide agonist of stromal cell-derived factor-1 (SDF-1), a key signaling molecule in the proliferation, homing, engraftment and expansion of hematopoietic stem cells and white blood cells.

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Inflammatory AgentsBiological Factors +8
Target Protein:
Stromal cell-derived factor 1
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CTCE-9908 DB05625
small molecule | CAS: 1030384-98-5

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and Proteins
Target Protein:
C-X-C chemokine receptor type 4
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CTI-1601 DB17010
biotech

Deskripsi belum tersedia.

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CTR-107 DB18583
biotech

CTR-107 is a synthetic targeted growth factor. It is being investigated for the treatment of familial exudative vitreoretinopathy.

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CTS-1027 DB08490
small molecule | CAS: 193022-04-7

CTS-1027 has been used in trials studying the treatment of Hepatitis C and Chronic Hepatitis C Virus Infection.

Kategori:
AminesHydroxy AcidsHydroxylamines
Target Protein:
Stromelysin-1Interstitial collagenase72 kDa type IV collagenase +2
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CTS-21166 DB06073
small molecule

CTS-21166 is a small-molecule beta-secretase inhibitor, which is being developed as a disease-modifying treatment for Alzheimer's disease. CTS-21166 is the only BACE1 inhibitor that has passed Phase I clinical trial thus far. In 2008, CoMentis revealed this s…

Target Protein:
Beta-secretase 1
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CTT-1057 DB14965
small molecule | CAS: 1628717-55-4

CTT-1057 is under investigation in clinical trial NCT03427476 (CTT1057, a Small Molecular Inhibitor of PSMA, as a Novel Imaging Agent of Neovascularization in Renal Cell Carcinoma).

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CTx-PDE6b DB17858
biotech

CTx-PDE6b is an adeno-associated virus (AAV) based gene therapy designed to deliver a full-length non-mutated copy of the functional human _PDE6b_ gene. Being commercialied by Coave Therapeutics, it is being investigated for the treatment of retinitis pigment…

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CTX110 DB18626
biotech

CTX110 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD19 antigen.

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CTX120 DB18625
biotech

CTX120 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting B-cell maturation antigen.

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CTX130 DB18627
biotech

CTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen.

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Cu-64 sartate DB18170
small molecule

Deskripsi belum tersedia.

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Cu-67 sartate DB18698
small molecule

Deskripsi belum tersedia.

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Cu-Cyclam DB03189
small molecule

Deskripsi belum tersedia.

Target Protein:
Lysozyme C
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CUDC-101 DB12174
small molecule | CAS: 1012054-59-9

CUDC-101 has been used in trials studying the treatment of Cancer, Tumors, Liver Cancer, Breast Cancer, and Gastric Cancer, among others.

Kategori:
AminesAntineoplastic AgentsHeterocyclic Compounds, Fused-Ring +5
Target Protein:
Epidermal growth factor receptorReceptor tyrosine-protein kinase erbB-2
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Cudetaxestat DB18203
small molecule | CAS: 1782070-21-6

Deskripsi belum tersedia.

Target Protein:
Autotaxin
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Cumidine DB02114
small molecule | CAS: 99-88-7

Deskripsi belum tersedia.

Kategori:
Amines
Target Protein:
Chymotrypsin-like elastase family member 1
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Cupric cation DB14552
small molecule | CAS: 15158-11-9

Deskripsi belum tersedia.

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Cupric Chloride Approved DB09131
small molecule | CAS: 7447-39-4

Cupric chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive to solutions for Total Parenteral Nutrition (TPN).

Kategori:
ElementsMetalsMetals, Heavy +1
Target Protein:
Vitamin K-dependent protein CCystatin-B
Waktu Paruh-
Vol. DistribusiCopper is distribut…
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small molecule | CAS: 13479-54-4

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, Peptides, and Proteins
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Cupric oxide Approved DB11134
small molecule | CAS: 1317-38-0

Cupric oxide, or copper (II) oxide, is an inorganic compound with the chemical formula CuO. Cupric oxide is used as a precursor in many copper-containing products such as wood preservatives and ceramics. Cupric oxide may be found in over-the-counter vitamin-m…

Kategori:
Diet, Food, and NutritionElementsFood +6
Waktu ParuhNo pharmacokinetic …
Vol. DistribusiFollowing exposure …
KlirensNo pharmacokinetic …
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Cupric sulfate Approved DB06778
small molecule | CAS: 7758-98-7

Cupric sulfate is a salt created by treating cupric oxide with sulfuric acid. This forms as large, bright blue crystals containing five molecules of water (CuSO4?5H2O) and is also known as _blue vitriol_. The anhydrous salt is created by heating the hydrate t…

Kategori:
AntidotesAutonomic AgentsCentral Nervous System Agents +10
Waktu ParuhThe biological half…
Vol. DistribusiThe body of a 70 kg…
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small molecule | CAS: 7758-89-6

Deskripsi belum tersedia.

Kategori:
ElementsMetalsMetals, Heavy +1
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CUR-1916 DB17838
biotech

Deskripsi belum tersedia.

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Curcuma aromatica root oil Approved DB11301
biotech | CAS: 94349-73-2

Curcuma aromatica root oil is obtained from the roots of *Curcuma aromatica*, or more commonly called wild tumeric, via steamed distillation. *Curcuma aromatica* belongs to the family Zingiberaceae. The wild ginger has been used as a cosmetic herbal where its…

Kategori:
Biological ProductsPlant OilsPlant Preparations
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biotech

_Curcuma xanthorrhiza_ oil is extracted from _Curcuma xanthorrhiza_ Roxb., a member of the ginger family (_Zingiberaceae_) that is widely distributed in the region of Southeastern Asia [A33162]. _Curcuma xanthorrhiza_ is also known as Javanese Turmeric or Te…

Waktu ParuhThere are no pharma…
Vol. DistribusiThere are no pharma…
KlirensThere are no pharma…
Genetik -
Curcumin Approved DB11672
small molecule | CAS: 458-37-7

Curcumin, also known as diferuloylmethane, is an active component in the golden spice turmeric (Curcuma longa) and in [Curcuma xanthorrhiza oil]. It is a highly pleiotropic molecule that exhibits antibacterial, anti-inflammatory, hypoglycemic, antioxidant, wo…

Kategori:
AlkanesAnalgesicsAnalgesics, Non-Narcotic +29
Target Protein:
Cytochrome P450 3A4Nitric oxide synthase, inducibleCarbonic anhydrase 14 +18
Waktu ParuhNo pharmacokinetic …
Vol. DistribusiFollowing oral admi…
KlirensNo pharmacokinetic …
Genetik -
small molecule | CAS: 339286-19-0

Deskripsi belum tersedia.

Kategori:
Cytochrome P-450 CYP1A2 InhibitorsCytochrome P-450 CYP1A2 Inhibitors (strength unknown)Cytochrome P-450 CYP2B6 Inhibitors +13
Target Protein:
Peroxisome proliferator-activated receptor gammaVitamin D3 receptorATP-binding cassette sub-family C member 5 +2
Waktu ParuhNo pharmacokinetic …
Vol. DistribusiFollowing oral admi…
KlirensNo pharmacokinetic …
Genetik -
Cusatuzumab DB15100
biotech | CAS: 1864871-20-4

CD70 is a ligand expressed on the surface of activated lymphocytes and mature dendritic cells that, in its binding to CD27 receptors, plays an important role in cell proliferation and survival. An overexpression of CD70 can result in the proliferation of mali…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodies, MonoclonalAntibodies, Monoclonal, Humanized +4
Target Protein:
CD70 antigen
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Custirsen DB05487
biotech | CAS: 890056-27-6

Custirsen is a benzopyran with potential antineoplastic activity. Custirsen acts as a selective estrogen receptor modulator (SERM), inhibiting the proliferation of estrogen-sensitive breast cancer cells. This agent also inhibits growth and induces apoptosis o…

Kategori:
Antisense OligonucleotidesHeterocyclic Compounds, Fused-RingNucleic Acids, Nucleotides, and Nucleosides +3
Target Protein:
ClusterinEstrogen receptorNuclear factor NF-kappa-B p100 subunit +1
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Cutamesine DB06618
small molecule | CAS: 165377-43-5

Deskripsi belum tersedia.

Kategori:
Central Nervous System AgentsNootropic AgentsReceptors, sigma, agonists
Target Protein:
Sigma non-opioid intracellular receptor 1
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CV-8102 DB19184
biotech

CV-8102 is under investigation in clinical trial NCT03203005 (IMA970A Plus CV8102 in Very Early, Early and Intermediate Stage Hepatocellular Carcinoma Patients).

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CV-MG01 DB16994
biotech

Deskripsi belum tersedia.

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CVN-424 DB18958
small molecule | CAS: 2254706-21-1

CVN-424 is under investigation in clinical trial NCT06006247 (Early Parkinson's Disease Monotherapy With CVN424).

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CVnCoV DB15844
biotech

The CVnCov Vaccine (or CV07050101) is in development by CureVac AG. The vaccine uses mRNA technology to create a protein associated with SARS-CoV2, and upon administration and replication, to initiate subsequent immune responses in the body. As of June 2020, …

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CVnCoV Vaccine DB15843
biotech

The CVnCov Vaccine (or CV07050101) is in development by CureVac AG. The vaccine uses mRNA technology to create a protein associated with SARS-CoV2, and upon administration and replication, to initiate subsequent immune responses in the body. As of June 2020, …

Kategori:
Amino Acids, Peptides, and ProteinsAntigensBiological Factors +10
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CVT-6883 DB05936
small molecule | CAS: 752222-83-6

CVT-6883 is a selective, potent and orally available A2B-adenosine receptor antagonist which CV Therapeutics is investigating for the potential treatment of asthma and other conditions related to inflammation and fibrosis.

Kategori:
Adenosine A2 Receptor AntagonistsHeterocyclic Compounds, Fused-Ring
Target Protein:
Adenosine receptor A2b
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CX-046684 Approved DB19414
biotech

CX-046684 is a COVID-19 mRNA vaccine encoding the pre-fusion stabilized Spike glycoprotein (S) of the SARS-CoV-2 Omicron variant lineage KP.2. It is the active ingredient of the 2024-2025 formulation of Moderna's Spikevax vaccine.[L40074]

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