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11778

Total database: 17430
Struktur (SMILES)
8554 (72.6%)
Target
6383 (54.2%)
Genomik
96 (0.8%)
Referensi
11778 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (11778)

Halaman 112 / 236
small molecule

Deskripsi belum tersedia.

Target Protein:
1-phosphatidylinositol phosphodiesterase
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Glucose oxidase DB12862
biotech | CAS: 9001-37-0

Glucose oxidase has been investigated for the treatment of Upper Respiratory Tract Infections.

Kategori:
Alcohol OxidoreductasesEnzymesEnzymes and Coenzymes +1
Waktu Paruh-
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Genetik -
small molecule | CAS: 56-73-5

An ester of glucose with phosphoric acid, made in the course of glucose metabolism by mammalian and other cells. It is a normal constituent of resting muscle and probably is in constant equilibrium with fructose-6-phosphate. (Stedman, 26th ed)

Kategori:
CarbohydratesGlucosephosphatesHexosephosphates +1
Target Protein:
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]Glucose-6-phosphate isomerase
Waktu Paruh-
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Genetik -
Glufosfamide DB06177
small molecule | CAS: 132682-98-5

Deskripsi belum tersedia.

Kategori:
CarbohydratesHexosesHydrocarbons, Halogenated +7
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Glumetinib DB15630
small molecule | CAS: 1642581-63-2

Glumetinib is under investigation in clinical trial NCT04270591 (Assess the Anti-tumor Activity and Safety of Glumetinib in Patient With Advanced C-met-positive Non-small Cell Lung Cancer).

Waktu Paruh-
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small molecule | CAS: 80143-57-3

Glutamine 2-n-15 is under investigation in clinical trial NCT01912235 (Arginine Synthesis in Healthy Adult Humans).

Waktu Paruh-
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Genetik -
small molecule | CAS: 1955-67-5

Deskripsi belum tersedia.

Kategori:
AminesAmino AcidsAmino Acids, Acidic +5
Target Protein:
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Glutamyl Group DB03774
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
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Glutathione Approved DB00143
small molecule | CAS: 70-18-8

A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.

Kategori:
Amino Acids, Peptides, and ProteinsAntidotesDietary Supplements +4
Target Protein:
Aldo-keto reductase family 1 member B1Matrix metalloproteinase-9Cytochrome P450 3A4 +38
Waktu Paruh-
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Genetik -
Glutathione disulfide Approved DB03310
small molecule | CAS: 27025-41-8

A GLUTATHIONE dimer formed by a disulfide bond between the cysteine sulfhydryl side chains during the course of being oxidized.

Kategori:
Amino Acids, Peptides, and ProteinsOligopeptidesPeptides
Target Protein:
Glutathione peroxidaseMicrosomal glutathione S-transferase 1Glutathione S-transferases (Cytosolic) +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Glutathione S-transferase kappa 1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule | CAS: 3773-07-7

Deskripsi belum tersedia.

Target Protein:
Glutathione S-transferase Mu 4Glutathione S-transferase A1Glutathione S-transferase P +1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Glutazumab DB16697
biotech

Glutazumab is a novel long-lasting GLP-1/anti-GLP-1R antibody fusion protein exerting anti-diabetic effects.[A235745]

Kategori:
Blood Glucose Lowering Agents
Target Protein:
Glucagon-like peptide 1 receptor
Waktu Paruh-
Vol. Distribusi-
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Glutethimide Approved DB01437
small molecule | CAS: 77-21-4

Glutethimide is a hypnotic and sedative. Its use has been largely superseded by other drugs.

Kategori:
Central Nervous System AgentsCentral Nervous System DepressantsHypnotics and Sedatives +5
Target Protein:
Gamma-aminobutyric acid receptor subunit alpha-1Cytochrome P450 2D6GABA(A) Receptor
Waktu Paruh10-12 hours
Vol. Distribusi-
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Genetik -
Glyburide Approved DB01016
small molecule | CAS: 10238-21-8

Glyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II.[L8123] It is typically given to patients who cannot be managed with the standard first line therapy, [metformin].[L8123] Glyburide stimulates insulin secretio…

Kategori:
Alimentary Tract and MetabolismAmidesBCRP/ABCG2 Substrates +28
Target Protein:
ATP-binding cassette sub-family C member 8Sulfonylurea receptor 1, Kir6.2ATP-binding cassette sub-family C member 9 +6
Waktu ParuhElderly patients ha…
Vol. DistribusiElderly patients ha…
KlirensElderly patients ha…
Genetik -
biotech

Deskripsi belum tersedia.

Kategori:
Aldehyde OxidoreductasesEnzymesEnzymes and Coenzymes +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 17181-54-3

Deskripsi belum tersedia.

Kategori:
AlcoholsCarbohydratesLipids +5
Target Protein:
Triosephosphate isomerase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 111-03-5

Deskripsi belum tersedia.

Kategori:
Lipids
Target Protein:
Glucose-dependent insulinotropic receptor
Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule | CAS: 27215-38-9

Deskripsi belum tersedia.

Kategori:
Cariostatic AgentsCompounds used in a research, industrial, or household settingFatty Acids +5
Waktu Paruh-
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Glyceryl monocaprylate Approved DB19362
small molecule | CAS: 26402-26-6

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicFatty AcidsLipids +1
Waktu Paruh-
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Genetik -
small molecule | CAS: 2752-99-0

Glyceryl Trierucate has been investigated for the treatment of Adrenoleukodystrophy.

Waktu Paruh-
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small molecule | CAS: 122-32-7

Glyceryl Trioleate has been investigated for the treatment of Adrenoleukodystrophy.

Kategori:
FatsFats, UnsaturatedGlycerides +2
Waktu Paruh-
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Genetik -
small molecule | CAS: 640-79-9

A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic. [PubChem]

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsBile Acids and Salts +12
Target Protein:
7-alpha-hydroxysteroid dehydrogenase
Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule | CAS: 475-31-0

The glycine conjugate of cholic acid. It acts as a detergent to solubilize fats for absorption and is itself absorbed.

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsBile Acids and Salts +11
Target Protein:
Gastrotropin
Waktu Paruh-
Vol. Distribusi-
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Glycocyamine DB02751
small molecule | CAS: 352-97-6

Deskripsi belum tersedia.

Kategori:
Affinity LabelsAmino AcidsAmino Acids, Peptides, and Proteins +3
Target Protein:
Guanidinoacetate N-methyltransferase
Waktu Paruh-
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Glycol salicylate Approved DB11323
small molecule | CAS: 87-28-5

Glycol salicylate, also known as _2-hydroxyethyl salicylate_, is a benzoate ester formed from the condensation of the carboxy group of salicylic acid with one of the hydroxy groups of ethylene glycol. It is found as an active ingredient and topical analgesic …

Kategori:
Acids, CarbocyclicAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-Steroidal +5
Target Protein:
Prostaglandin G/H synthase 1Prostaglandin G/H synthase 2
Waktu ParuhThe serum half-life…
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Glycolic acid Approved DB03085
small molecule | CAS: 79-14-1

Deskripsi belum tersedia.

Kategori:
AcetatesAcids, AcyclicDermatologicals +2
Target Protein:
Glucose-6-phosphate 1-dehydrogenase
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Glycopyrronium Approved DB00986
small molecule | CAS: 740028-90-4

Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers.[L33110] They are both quaternary ammonium compounds and long acting muscarinic antagonists.[L33110] It is one of the most commonly prescribed anticholinergic medi…

Kategori:
Adjuvants, AnesthesiaAdrenergics, InhalantsAgents producing tachycardia +30
Target Protein:
Muscarinic acetylcholine receptor M1Muscarinic acetylcholine receptor M3Muscarinic acetylcholine receptor M2 +2
Waktu ParuhThe half life after…
Vol. DistribusiThe mean volume of …
KlirensA 6 µg/kg intraveno…
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
D-alanyl-D-alanine carboxypeptidase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Prolyl tripeptidyl peptidase
Waktu Paruh-
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Genetik -
Glycylglutamine DB15990
small molecule | CAS: 13115-71-4

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsNeural InhibitionOligopeptides +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Glycyltyrosine DB15991
small molecule | CAS: 658-79-7

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsOligopeptidesPeptides
Waktu Paruh-
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Genetik -
Glycyrrhiza glabra Approved DB14312
biotech | CAS: 84775-66-6

Glycyrrhiza glabra is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Kategori:
AngiospermsBiological ProductsCell-mediated Immunity +12
Waktu Paruh-
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Genetik -
Glycyrrhizic acid Approved DB13751
small molecule | CAS: 1405-86-3

Glycyrrhizic acid is extracted from the root of the licorice plant; _Glycyrrhiza glabra_.[F79] It is a triterpene glycoside with glycyrrhetinic acid that possesses a wide range of pharmacological and biological activities. When extracted from the plant, it ca…

Kategori:
Alimentary Tract and MetabolismAnti-Inflammatory AgentsBile and Liver Therapy +6
Target Protein:
11-beta-hydroxysteroid dehydrogenase 1Tumor necrosis factorCaspase-3 +2
Waktu ParuhDepending on the do…
Vol. DistribusiThe apparent volume…
KlirensThe constant reabso…
Genetik -
Glyphosate DB04539
small molecule | CAS: 1071-83-6

Deskripsi belum tersedia.

Kategori:
AgrochemicalsAmino AcidsAmino Acids, Peptides, and Proteins +9
Target Protein:
Aromatase3-phosphoshikimate 1-carboxyvinyltransferase3-phosphoshikimate 1-carboxyvinyltransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Glypromate DB05633
small molecule | CAS: 32302-76-4

Neuren Pharmaceuticals was developing Glypromate (glycine-proline glutamate), a naturally occurring small-molecule neuroprotectant derived from IGF-1 which inhibits caspase III dependent apoptosis, for the potential treatment of neurodegenerative diseases by …

Kategori:
Amino Acids, Peptides, and ProteinsPeptides
Waktu Paruh-
Vol. Distribusi-
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Genetik -
GMA-161 DB15397
biotech | CAS: 946415-70-9

GMA-161 is under investigation in clinical trial NCT00244257 (Safety Study of GMA161 in Patients With Idiopathic Thrombocytopenic Purpura (ITP)).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +6
Waktu Paruh-
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Genetik -
GMX1777 DB05217
small molecule

GMX1777 is a water-soluble prodrug of the cyanoguanidine compound GMX1778 with potential antineoplastic activity. In vivo, apoptosis inducer GMX1777 is rapidly converted into GMX1778 through hydrolytic cleavage of a carbonate ester bond. Although the exact me…

Kategori:
Amidines
Target Protein:
Nicotinamide phosphoribosyltransferase
Waktu Paruh-
Vol. Distribusi-
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Genetik -
GO-203-2C DB15008
small molecule | CAS: 1469735-88-3

GO-203-2C is under investigation in clinical trial NCT02204085 (A Phase I/II Trial of the MUC1 Inhibitor, GO-203-2C in Patients With Relapsed or Refractory Acute Myeloid Leukemia).

Waktu Paruh-
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Go-6976 DB17029
small molecule | CAS: 136194-77-9

An inhibitor of calcium-dependent isoforms of protein kinase C.[A253002,A253007]

Kategori:
Enzyme InhibitorsHeterocyclic Compounds, Fused-RingIndoles +1
Target Protein:
Transcription factor RelBNuclear factor NF-kappa-B p105 subunitNuclear factor NF-kappa-B p100 subunit +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Golcadomide DB18115
small molecule | CAS: 2379572-34-4

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Gold DB14154
small molecule | CAS: 7440-57-5

A yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in t…

Kategori:
Cell-mediated ImmunityElementsGold Compounds +5
Waktu Paruh-
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Klirens-
Genetik -
Gold Au-198 DB13427
small molecule | CAS: 10043-49-9

Deskripsi belum tersedia.

Kategori:
Anti-Inflammatory AgentsElementsGold Isotopes +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 15283-45-1

Deskripsi belum tersedia.

Kategori:
Antirheumatic AgentsGold CompoundsSodium Compounds +5
Waktu Paruh-
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Klirens-
Genetik -
Golexanolone DB18200
small molecule | CAS: 2089238-18-4

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Golidocitinib DB18057
small molecule | CAS: 2091134-68-6

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
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Genetik -
Golimumab Approved DB06674
biotech | CAS: 476181-74-5

Golimumab is a human IgG1? monoclonal antibody derived from immunizing genetically engineered mice with human TNF?. Golimumab binds and inhibits soluble and transmembrane human TNF?. Increased TNF? is associated with chronic inflammation. Thus golimumab is in…

Kategori:
Agents reducing cytokine levelsAmino Acids, Peptides, and ProteinsAnti-Inflammatory Agents +17
Target Protein:
Tumor necrosis factor
Waktu ParuhGolimumab has a lon…
Vol. DistribusiAfter IV administra…
KlirensAfter one IV dose o…
Genetik -
biotech | CAS: 957472-14-9

Deskripsi belum tersedia.

Kategori:
Gene Transfer TechniquesNucleic AcidsNucleic Acids, Nucleotides, and Nucleosides
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Golodirsen Approved DB15593
biotech | CAS: 1422959-91-8

Golodirsen is a morpholino antisense oligomer designed to treat about 8% of patients with Duchenne Muscular Dystrophy (DMD). This is an X-linked condition leading to progressive muscle degeneration that begins in early childhood, rendering many patients wheel…

Kategori:
Antisense Elements (Genetics)Antisense OligonucleotidesCompounds used in a research, industrial, or household setting +10
Target Protein:
Dystrophin
Waktu ParuhIn a pharmacokineti…
Vol. DistribusiThe volume of distr…
KlirensThis drug is rapidl…
Genetik -
Golotimod DB05475
small molecule | CAS: 229305-39-9

SCV-07 (g -D-glutamyl-L-tryptophan) is a novel synthetic dipeptide that acts broadly on the Toll-like receptor pathway. It has been shown to stimulate T-lymphocyte differentiation, macrocytic phagocytosis, and specific immune responses, and enhance IL-2 and …

Kategori:
Amino Acids, Peptides, and ProteinsOligopeptidesPeptides
Target Protein:
Signal transducer and activator of transcription 3Toll-like receptor 2Toll-like receptor 4 +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
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