Hasil Filter

17430

Total database: 17430
Struktur (SMILES)
12313 (70.6%)
Target
9368 (53.7%)
Genomik
112 (0.6%)
Referensi
17430 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (17430)

Halaman 109 / 349
small molecule | CAS: 227016-66-2

CH-1504 L-isomer is under investigation in clinical trial NCT01116141 (A Study of CH-4051 in Patients With Rheumatoid Arthritis (RA)).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CH-5132799 DB13051
small molecule | CAS: 1007207-67-1

CH5132799 has been used in trials studying the treatment of Solid Tumors.

Kategori:
AmidesClass I Phosphatidylinositol 3-Kinases, antagonists & inhibitorsSulfones +1
Target Protein:
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chaetomium globosum Approved DB10430
biotech

Chaetomium globosum is a fungus which can provoke allergic reactions. Chaetomium globosum extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Chamaecyparis obtusa wood oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Chamaemelum nobile flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Kategori:
AngiospermsAsteraceaeBiological Products +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chamazulene DB15931
small molecule | CAS: 529-05-5

Deskripsi belum tersedia.

Kategori:
CycloheptanesCycloparaffins
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chamomile Approved DB14357
biotech

Chamomile is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Kategori:
AngiospermsAsteraceaeBiological Products +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Channel catfish Approved DB15548
biotech

Channel catfish allergenic extract is used in allergenic testing.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chelerythrine DB17024
small molecule | CAS: 34316-15-9

A benzophenanthridine alkaloid evaluated as a kinase-inhibitor.[A252982]

Kategori:
AlkaloidsAnti-Bacterial AgentsAnti-Infective Agents +4
Target Protein:
P2X purinoceptor 7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chenodeoxycholic acid Approved DB06777
small molecule | CAS: 474-25-9

Chenodeoxycholic acid (or Chenodiol) is an epimer of ursodeoxycholic acid (DB01586). Chenodeoxycholic acid is a bile acid naturally found in the body. It works by dissolving the cholesterol that makes gallstones and inhibiting production of cholesterol in the…

Kategori:
Alimentary Tract and MetabolismBile Acid PreparationsBile acids and derivatives +12
Target Protein:
Bile acid receptorNuclear receptor subfamily 1 group I member 2G-protein coupled bile acid receptor 1 +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chenopodium album pollen Approved DB10368
biotech

Chenopodium album pollen is the pollen of the Chenopodium album plant. Chenopodium album pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Chenopodium ambrosioides pollen is the pollen of the Chenopodium ambrosioides plant. Chenopodium ambrosioides pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chenopodium botrys pollen Approved DB10838
biotech

Chenopodium botrys pollen is the pollen of the Chenopodium botrys plant. Chenopodium botrys pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Cherry Approved DB10518
biotech

Cherry allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CHF 4227 DB05882
small molecule

CHF 4227 is a new selective estrogen receptor modulator (SERM). The compound has a high receptor affinity and has shown promising efficacy in the prevention of bone loss in animal models of osteoporosis. Additionally, the compound has shown no uterotrophic ac…

Kategori:
Heterocyclic Compounds, Fused-RingPyrans
Target Protein:
Estrogen receptorEstrogen receptor beta
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CHF-6001 DB12800
small molecule | CAS: 1239278-59-1

CHF6001 has been used in trials studying the treatment of Asthma and Chronic Obstructive Pulmonary Disease.

Kategori:
Acids, CarbocyclicAmidesAminobenzoates +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CHF-6333 DB17815
small molecule | CAS: 1613621-54-7

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CHF5633 DB18696
biotech

CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl?oleoyl?phosphatidylglycerol sodium), a synthetic SP-C analogue, and a synthetic SP-B analogue.

Kategori:
Amino Acids, Peptides, and ProteinsGlycerophosphatesGlycerophospholipids +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CHGN111 DB06376
small molecule

CHGN111 is an inhibitor of the mitochondrial enzyme CLK-1 which is a demethoxyubiquinone hydroxylase. Numerous parameters of mitochondrial function are altered when the activity of CLK-1 is reduced, which results in a decrease of ROS at critical cellular site…

Target Protein:
Dual specificity protein kinase CLK1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chiauranib DB16124
small molecule | CAS: 1256349-48-0

Chiauranib is under investigation in clinical trial NCT03974243 (Chiauranib in Combination With Chidamide in Patients With Relapsed/refractory Non-hodgkin's Lymphoma).

Kategori:
Antineoplastic AgentsEnzyme InhibitorsHeterocyclic Compounds, Fused-Ring +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chicken Approved DB10519
biotech

Chicken allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chickpea Approved DB10662
biotech

Chickpea allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chicory leaf DB14376
biotech

Chicory leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chiglitazar DB19023
small molecule | CAS: 743438-45-1

Chiglitazar is under investigation in clinical trial NCT06125587 (Chiglitazar/metformin in Non-obese Women With PCOS).

Kategori:
Acids, AcyclicFatty AcidsFatty Acids, Volatile +3
Target Protein:
Peroxisome proliferator-activated receptor gammaPeroxisome proliferator-activated receptor alpha
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Chikungunya virus (CHIKV) is a member of the Alphavirus genus that was first identified in Tanzania in 1952.[A262051] It is spread primarily by the bite of infected mosquitos of the _Aedes_ genus. Infection with CHIKV causes chikungunya fever, an illness char…

Kategori:
Live vaccinesVaccinesViral Vaccines
Waktu ParuhThere is limited ph…
Vol. DistribusiThere is limited ph…
KlirensThere is limited ph…
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chiniofon DB13379
small molecule | CAS: 8002-90-2

Deskripsi belum tersedia.

Kategori:
Antiparasitic Products, Insecticides and RepellentsAntiprotozoalsHeterocyclic Compounds, Fused-Ring +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CHIR-124 DB06852
small molecule | CAS: 405168-58-3

CHIR-124 is a potent inhibitor of Chk1 that potentiates the cytotoxicity of topoisomerase I poisons in vitro and in vivo.

Kategori:
Heterocyclic Compounds, Fused-Ring
Target Protein:
Serine/threonine-protein kinase Chk1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chitin DB15142
small molecule | CAS: 1398-61-4

Shrimp shell chitin is under investigation in clinical trial NCT00863356 (Trial of a Novel Chitosan Hemostatic Sealant in the Management of Complicated Epistaxis).

Kategori:
BiopolymersCarbohydratesChitin, antagonists & inhibitors +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 9012-76-4

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chloral betaine DB01494
small molecule | CAS: 2218-68-0

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chloral hydrate Approved DB01563
small molecule | CAS: 302-17-0

A hypnotic and sedative used in the treatment of insomnia. The safety margin is too narrow for chloral hydrate to be used as a general anesthetic in humans, but it is commonly used for that purpose in animal experiments. It is no longer considered useful as a…

Kategori:
AlcoholsCentral Nervous System AgentsCentral Nervous System Depressants +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chlorambucil Approved DB00291
small molecule | CAS: 305-03-3

A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Repor…

Kategori:
Agents that reduce seizure thresholdAlkylating ActivityAlkylating Drugs +12
Target Protein:
DNA
Waktu Paruh1.5 hours
Vol. Distribusi-
Klirens-
Genetik -
Chloramphenicol Approved DB00446
small molecule | CAS: 56-75-7

An antibiotic first isolated from cultures of _Streptomyces venezuelae_ in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein sy…

Kategori:
AlcoholsAmphenicolsAnti-Acne Preparations +34
Target Protein:
50S ribosomal protein L16Dr hemagglutinin structural subunitComplement decay-accelerating factor
Waktu ParuhHalf-life in adults…
Vol. Distribusi-
Klirens-
Genetik -
Chloramphenicol palmitate Approved DB14658
small molecule | CAS: 530-43-8

Deskripsi belum tersedia.

Kategori:
AlcoholsBenzene DerivativesGlycols +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chloramphenicol succinate Approved DB07565
small molecule | CAS: 3544-94-3

Chloramphenicol succinate is an ester prodrug of [chloramphenicol].[A192987] Chloramphenicol is a bacteriostatic antibiotic.[A204065] Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially fatal blood dyscrasias.[L14…

Kategori:
AlcoholsAnti-Bacterial AgentsAnti-Infective Agents +8
Target Protein:
Dr hemagglutinin structural subunit
Waktu ParuhThe half life of ch…
Vol. DistribusiChloramphenicol suc…
KlirensChloramphenicol suc…
Genetik -
small molecule | CAS: 522-18-9

Deskripsi belum tersedia.

Kategori:
Alimentary Tract and MetabolismDrugs for Functional Gastrointestinal Disorders
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chlorcyclizine Approved DB08936
small molecule | CAS: 82-93-9

Chlorcyclizine is a first generation phenylpiperazine class antihistamine used to treat urticaria, rhinitis, pruritus, and other allergy symptoms. Chlorcyclizine also has some local anesthetic, anticholinergic, and antiserotonergic properties, and can be used…

Kategori:
Antihistamines for Systemic UseHistamine AntagonistsHistamine H1 Antagonists +3
Target Protein:
Histamine H1 receptor
Waktu Paruhabout 12 h.
Vol. DistribusiAfter a single oral…
Klirens-
Genetik -
Chlordiazepoxide Approved DB00475
small molecule | CAS: 58-25-3

An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.

Kategori:
Adjuvants, AnesthesiaAnti-Anxiety AgentsBenzazepines +22
Target Protein:
Translocator proteinGABA(A) ReceptorGABA(A) Receptor Benzodiazepine Binding Site
Waktu Paruh24-48 hours
Vol. Distribusi-
Klirens-
Genetik -
Chlorfenson DB05377
small molecule | CAS: 80-33-1

Chlorfenson is developed by Moberg Derma for the treatment of onychomycosis (nail fungus) as the primary indication.

Kategori:
ArylsulfonatesArylsulfonic AcidsBenzene Derivatives +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chlorhexadol DB01534
small molecule | CAS: 3563-58-4

Chlorhexadol is a sedative and hypnotic which is regulated in the United States as a Schedule III controlled substance. It is a derivative of chloral hydrate.

Kategori:
AldehydesCentral Nervous System DepressantsHypnotics and Sedatives +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chlorhexidine Approved DB00878
small molecule | CAS: 55-56-1

Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms.[L11512] It is one of the most common skin and mucous membrane antisepti…

Kategori:
Alimentary Tract and MetabolismAmidinesAnti-Infective Agents +25
Target Protein:
Bacterial outer membrane
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chloric acid Approved DB14150
small molecule | CAS: 7790-93-4

Deskripsi belum tersedia.

Kategori:
AgrochemicalsAnionsChlorine Compounds +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chloride ion DB14547
small molecule | CAS: 16887-00-6

Deskripsi belum tersedia.

Kategori:
AnionsChloridesChlorine Compounds +2
Target Protein:
Lanosterol 14-alpha demethylase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chlorindanol DB19355
small molecule | CAS: 145-94-8

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chlorine DB11109
small molecule | CAS: 7782-50-5

Chlorine is a stongly oxidizing agent and the third most electronegative element which belongs to the group of halogens with the atomic number 17 and symbol Cl. Being a yellow-green gas at room temperature, chlorine is the second most abundant halogen on Eart…

Kategori:
Compounds used in a research, industrial, or household settingElementsGases +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 10049-04-4

Chlorine Dioxide has been used in trials studying the treatment of Halitosis.

Kategori:
AnionsAnti-Infective AgentsCompounds used in a research, industrial, or household setting +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Chlorisondamine Approved DB19358
small molecule | CAS: 7701-62-4

Deskripsi belum tersedia.

Kategori:
AminesAnticholinergic AgentsAntihypertensive Agents +12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 5401–5450 dari 17430
Sebelumnya Halaman 109 / 349 Berikutnya