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15718

Total database: 17430
Struktur (SMILES)
10762 (68.5%)
Target
7957 (50.6%)
Genomik
112 (0.7%)
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15718 (100.0%)

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Hasil Pencarian (15718)

Halaman 102 / 315
biotech

COVID-19 convalescent plasma is plasma collected from patients who have acquired and subsequently recovered from COVID-19 and which contains antibodies against the causative agent SARS-CoV-2.[L14333] This investigational COVID-19 treatment is currently availa…

Kategori:
Experimental Unapproved Treatments for COVID-19
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biotech

Through analysis of potential immunogenic targets of the SARS-Cov2 genome, a synthetic ‘minigene’ was developed using domains of viral structural proteins and a polyprotein protease. Specifically, the COVID-19 infection relies on the binding of the Spike prot…

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biotech

As of July 2020, Medicine Invention Design, Inc. is sponsoring a small, controlled clinical trial for the COVID-19 AP TP Vaccine for ‘proof of concept.’ The vaccine utilizes granulocyte macrophage-colony stimulating factor (GM-CSF), a cytokine known to enhanc…

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biotech

COVID-19 Spike-GM-CSF Protein Lactated Ringer's Injection is an intradermal injection currently being investigated in the clinical trial NCT03348670 (Discovery Stage (Proof-of-concept) COVID-19 Antigen Presentation Therapeutic Biologics (COVID-19--AP) (AP-TP-…

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biotech

Dendritic cells (DCs) can be derived and differentiated from peripheral blood mononuclear cells in the presence of specific cytokines and growth factors. These cells are then loaded with antigens produced by a virus or tumor cell and administered as a vaccine…

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CoviGlobulin DB15747
biotech

CoviGlobulin, a rabbit polyclonal antibody, was specifically designed as a potential therapy for COVID-19. Rabbit polyclonal antibodies are derived from the rabbit, a common animal host for polyclonal production. The antibodies themselves are produced in resp…

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Cow milk Approved DB10543
biotech | CAS: 8049-98-7

Cow milk allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
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CP-12 DB18169
small molecule

Deskripsi belum tersedia.

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CP-122721 DB05421
small molecule | CAS: 145742-28-5

CP-122721, neurokinin 1 (NK1) antagonist is developed by Pfizer to treat depression, emesis, and inflammatory diseases including asthma and irritable bowel syndrome.

Target Protein:
Substance-P receptor
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small molecule

Deskripsi belum tersedia.

Target Protein:
Sorbitol dehydrogenase
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CP-195543 DB13053
small molecule | CAS: 204981-48-6

CP-195,543 has been used in trials studying the treatment of Arthritis, Rheumatoid.

Kategori:
BenzopyransHeterocyclic Compounds, Fused-RingPyrans
Target Protein:
Leukotriene B4 receptor 1
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CP-271485 DB02118
small molecule | CAS: 35580-46-2

Deskripsi belum tersedia.

Target Protein:
Macrophage metalloelastase
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CP-320626 DB03383
small molecule | CAS: 186430-23-9

Deskripsi belum tersedia.

Kategori:
Enzyme InhibitorsHeterocyclic Compounds, Fused-RingPhosphorylase b, antagonists & inhibitors
Target Protein:
Lanosterol 14-alpha demethylaseGlycogen phosphorylase, muscle form
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CP-39,332 DB09193
small molecule | CAS: 61764-60-1

CP-39,332 is a serotonin-norepinephrine reuptake inhibitor (SNRI). It is part of a group of monoamine reuptake inhibitor stereoisomers including tametraline (1R,4S-), CP-24,442 (1S,4R-), CP-22,185 (cis-), and CP-22,186 that show varying efficiency. However, n…

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CP-526423 DB02089
small molecule

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-Ring
Target Protein:
Glycogen phosphorylase, liver form
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CP-547632 DB12962
small molecule | CAS: 252003-65-9

CP-547632 has been used in trials studying the treatment of Ovarian Cancer, Lung Neoplasms, Ovarian Neoplasms, Peritoneal Neoplasms, and Fallopian Tube Cancer, among others.

Kategori:
AmidesSulfur Compounds
Target Protein:
Vascular endothelial growth factor receptor 2
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CP-601927 DB12244
small molecule | CAS: 357425-02-6

CP-601,927 has been used in trials studying the basic science and treatment of Major Depressive Disorder.

Target Protein:
Neuronal acetylcholine receptor subunit alpha-4Neuronal acetylcholine receptor subunit beta-2
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CP-609754 DB12640
small molecule | CAS: 1190094-64-4

LNK 754 has been investigated in Mild Alzheimer's Disease.

Kategori:
Heterocyclic Compounds, Fused-RingQuinolines
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CP-724714 DB12302
small molecule | CAS: 537705-08-1

CP-724,714 has been used in trials studying the treatment of Breast Cancer, Breast Neoplasms, and Neoplasm Metastasis.

Kategori:
Heterocyclic Compounds, Fused-RingReceptor, ErbB-2, antagonists & inhibitors
Target Protein:
Receptor tyrosine-protein kinase erbB-2
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CP-744809 DB07187
small molecule | CAS: 463976-07-0

Deskripsi belum tersedia.

Target Protein:
Aldo-keto reductase family 1 member B1
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CP-778875 DB19211
small molecule | CAS: 866355-28-4

CP-778875 is under investigation in clinical trial NCT00326326 (Effect of CP-778,875 on HDL-C in Subjects With Abnormal Lipid Levels and Type 2 Diabetes.).

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +2
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CP-866087 DB12196
small molecule | CAS: 519052-02-9

CP-866,087 has been used in trials studying the treatment of Obesity, Alcoholism, and Sexual Dysfunction, Physiological.

Kategori:
Aza Compounds
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CP-96345 DB16744
small molecule | CAS: 132746-60-2

Deskripsi belum tersedia.

Kategori:
AnalgesicsAnalgesics, Non-NarcoticAnti-Inflammatory Agents +9
Target Protein:
Substance-P receptor
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CP1-1189 DB12311
small molecule | CAS: 183619-38-7

CPI-1189 has been used in trials studying the treatment of HIV Infections and AIDS Dementia Complex.

Kategori:
AlkanesHydrocarbons, Acyclic
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Glycogen phosphorylase, liver form
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Cpad DB04071
small molecule

Deskripsi belum tersedia.

Target Protein:
Alcohol dehydrogenase 1C
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CPG 10101 DB05530
biotech | CAS: 957255-05-9

CPG 10101 is a synthetic oligodeoxynucleotide (ODN) in clinical trials. It is a toll-like receptor 9 (TLR9) agonist with antiviral and immunomodulatory properties that could potentially influence chronic infection with HCV.

Kategori:
Nucleic Acids, Nucleotides, and NucleosidesNucleotidesOligonucleotides +1
Target Protein:
Toll-like receptor 9
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CPG-52852 DB12476
small molecule | CAS: 532959-63-0

852A has been used in trials studying the treatment of Melanoma, Neoplasms, Breast Cancer, Ovarian Cancer, and Cervical Cancer, among others.

Target Protein:
Toll-like receptor 7
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CPGJ602 DB17485
biotech

CPGJ602 is a recombinant anti-EGFR human-mouse chimeric monoclonal antibody.

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CPI-006 DB16488
biotech | CAS: 2451856-97-4

CPI-006 was investigated in clinical trials NCT03454451, NCT04464395, and NCT04734873 to evaluate its safety and efficacy. NCT03454451 focused on advanced cancers (e.g., non-small cell lung cancer, renal cell cancer, colorectal cancer). NCT04464395 and NCT047…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
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CPI-1205 DB14581
small molecule | CAS: 1621862-70-1

Potent and selective histone methyltransferase EZH2 inhibitor.

Kategori:
Enzyme InhibitorsHeterocyclic Compounds, Fused-Ring
Target Protein:
Histone-lysine N-methyltransferase EZH2
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CPO-107 DB18492
biotech

CPO-107 is a CD20-CD47 bispecific fusion protein

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small molecule | CAS: 640897-20-7

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, CyclicAmino Acids, Peptides, and Proteins +1
Target Protein:
4-aminobutyrate aminotransferase, mitochondrial
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CPZEN-45 DB18077
small molecule | CAS: 737759-36-3

Deskripsi belum tersedia.

Kategori:
Drugs for Treatment of Tuberculosis
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CR002 DB05139
biotech

CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived growth factor-D (PDGF-D), a target shown to play a role in kidney inflammation. This is a novel therapeutic approach to treat kidney inflammat…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +6
Target Protein:
Platelet-derived growth factor D
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CR6086 DB16111
small molecule | CAS: 1417742-86-9

CR6086 is under investigation in clinical trial NCT03163966 (A Study of the EP4 Antagonist CR6086 in Combination With Methotrexate, in Dmard-naïve Patients With Early Rheumatoid Arthritis).

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CR665 DB05155
small molecule | CAS: 228546-92-7

CR665 is the lead clinical development candidate from a series of highly selective peripheral kappa opioid receptor agonists. In preclinical studies, CR665 was highly selective for the peripheral kappa opioid receptor. Preclinical animal studies suggest that …

Kategori:
Amino Acids, Peptides, and ProteinsNerve Tissue ProteinsNeuropeptides +2
Target Protein:
Kappa-type opioid receptor
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CRA-028129 DB05951
small molecule

CRA-028129 is cathepsin S inhibitor which is under investigation for the treatment of psoriasis.

Target Protein:
Cathepsin S
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Crab leg Approved DB11011
biotech

Crab leg allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
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Cranberry Approved DB10631
biotech

Cranberry allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract +1
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CRA_10433 DB03173
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
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CRA_10655 DB02526
small molecule

Deskripsi belum tersedia.

Target Protein:
Urokinase-type plasminogen activatorSerine protease 1
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CRA_10656 DB04470
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
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CRA_10762 DB02366
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
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CRA_10972 DB02989
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
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CRA_10991 DB01771
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
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CRA_11092 DB03555
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
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CRA_1144 DB03643
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease hepsinSerine protease 1
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CRA_16847 DB02063
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
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CRA_17312 DB02084
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
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