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6694

Total database: 17430
Struktur (SMILES)
4518 (67.5%)
Target
3751 (56.0%)
Genomik
81 (1.2%)
Referensi
6694 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

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Hasil Pencarian (6694)

Halaman 101 / 134
Phenylalanine Approved DB00120
small molecule | CAS: 63-91-2

Phenylalanine is an essential aromatic amino acid that is a precursor of melanin, [dopamine], [noradrenalin] (norepinephrine), and [thyroxine].

Kategori:
Amino AcidsAmino Acids, AromaticAmino Acids, Cyclic +7
Target Protein:
Tyrosine 3-monooxygenaseTyrosine aminotransferaseLarge neutral amino acids transporter small subunit 2 +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Alpha-lytic protease
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 98-80-6

Deskripsi belum tersedia.

Kategori:
AcidsAcids, NoncarboxylicBoron Compounds
Target Protein:
Carbonic anhydrase 2Carbonic anhydrase 4Carbonic anhydrase 1 +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Phenylbutazone Approved DB00812
small molecule | CAS: 50-33-9

A drug that has anti-inflammatory, antipyretic, and analgesic activities. It is especially effective in the treatment of ankylosing spondylitis. It also is useful in rheumatoid arthritis and Reiter's syndrome (investigational indication). Although phenylb…

Kategori:
Agents causing hyperkalemiaAgents that produce hypertensionAnalgesics +28
Target Protein:
Prostaglandin G/H synthase 1Prostaglandin G/H synthase 2Prostacyclin synthase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Phenylbutyric acid Approved DB06819
small molecule | CAS: 1821-12-1

Phenylbutyric acid is a fatty acid and a derivative of [butyric acid] naturally produced by colonic bacteria fermentation. It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting as a chemical chaperone.[A249035]…

Kategori:
Acids, CarbocyclicAlimentary Tract and MetabolismAmmonium Ion Binding Activity +8
Target Protein:
Histone deacetylase 1Protein kinase C alpha typeAromatic-amino-acid aminotransferase +1
Waktu ParuhFollowing oral admi…
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 7060-39-1

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, AromaticAmino Acids, Cyclic +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 34420-17-2

Deskripsi belum tersedia.

Kategori:
AcidsAcids, NoncarboxylicBoron Compounds
Target Protein:
Carbonic anhydrase 2Carbonic anhydrase 1Chymotrypsinogen B
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Phenylethyl resorcinol Approved DB14120
small molecule | CAS: 85-27-8

A tyrosinase inhibitor with skin-lightening activity.

Kategori:
Benzene DerivativesPhenols
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Ferrichrome-iron receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 62-38-4

Phenylmercuric acetate is an organomercurial compound used as a fungicide and slimicide.[A253082]

Kategori:
AgrochemicalsCompounds used in a research, industrial, or household settingFungicides, Industrial +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Phenylphosphate DB03298
small molecule | CAS: 701-64-4

Deskripsi belum tersedia.

Kategori:
Organophosphorus Compounds
Target Protein:
Proto-oncogene tyrosine-protein kinase Src
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 156-06-9

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicKeto AcidsPyruvates
Target Protein:
Phenylalanine dehydrogenase2-Hydroxyacid oxidase 1Indole-3-pyruvate decarboxylase +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Phenyltoloxamine Approved DB11160
small molecule | CAS: 92-12-6

Phenyltoloxamine is an antihistamine drug with sedative and analgesic effects. It is a H1 receptor blocker and a member of the ethanolamine class of antihistaminergic drugs. It is available in combination products that also contain other analgesics and antitu…

Kategori:
Benzene Derivatives
Target Protein:
D(2) dopamine receptorD(1B) dopamine receptorD(1A) dopamine receptor +2
Waktu ParuhReadily accessible …
Vol. DistribusiReadily accessible …
KlirensReadily accessible …
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Immunoglobulin kappa constant
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Phenytoin Approved DB00252
small molecule | CAS: 57-41-0

Phenytoin is classified as a hydantoin derivative and despite its narrow therapeutic index, it is one of the most commonly used anticonvulsants.[A33595,A188832,A189219] Since it's introduction about 80 years ago, phenytoin has not only been established as an …

Kategori:
Agents Causing Muscle ToxicityAnti-epileptic AgentAnticonvulsants +77
Target Protein:
Sodium channel protein type 5 subunit alphaSodium channel protein type 1 subunit alphaVoltage-gated inwardly rectifying potassium channel KCNH2 +7
Gen Terkait:
CYP2C9 HLA-B
Waktu ParuhOral administration…
Vol. DistribusiThe volume of distr…
KlirensThe clearance of ph…
Genetik 2 Varian
Phloretic acid DB03897
small molecule | CAS: 501-97-3

Deskripsi belum tersedia.

Kategori:
Acids, Carbocyclic
Target Protein:
Tyrosine phenol-lyasePrephenate dehydrogenaseTyrosine phenol-lyase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Phloroglucinol DB12944
small molecule | CAS: 108-73-6

Phloroglucinol has been used in trials studying the diagnostic of Colonoscopy.

Kategori:
Alimentary Tract and MetabolismBenzene DerivativesCompounds used in a research, industrial, or household setting +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Phloxine B Approved DB13911
small molecule | CAS: 18472-87-2

Phloxine B (commonly known simply as phloxine, also known as D&C RED NO. 28) is a color additive which is used both as an inactive ingredient to provide color to products, or as a colorant in dental disclosing tablets. These tablets allow patients to visualis…

Kategori:
Coloring AgentsCompounds used in a research, industrial, or household settingDental Agents +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Pholcodine Approved DB09209
small molecule | CAS: 509-67-1

Pholcodine formula is 3-o-morpholinoethylmorphine and it is classified as an antitussive which is defined as an opioid cough suppressant. It belongs to the opioid family of compounds and it is widely used.[A31738] Pholcodine activity is the suppression of unp…

Kategori:
AlkaloidsAnalgesicsAntitussive Agents +13
Target Protein:
Mu-type opioid receptorKappa-type opioid receptorDelta-type opioid receptor
Waktu ParuhAfter oral administ…
Vol. DistribusiThe reported volume…
KlirensAfter oral administ…
Genetik -
Phosmet DB11448
small molecule | CAS: 732-11-6

Phosmet is a phthalimide-derived organophosphate. It is a non-specific insecticide. It is mainly used on apple trees to control codling moths. It is also used on other fruit crops, ornamentals, and vines to control aphids, suckers, mites, and fruit flies.

Kategori:
AgrochemicalsCompounds used in a research, industrial, or household settingHeterocyclic Compounds, Fused-Ring +12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 34273-04-6

A non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It binds tightly to G-protein in the presence of Mg2+. The nucleotide is a potent stimulator of adenylate cyclase.

Kategori:
Guanine NucleotidesGuanosine TriphosphateHeterocyclic Compounds, Fused-Ring +5
Target Protein:
Ras-related protein Rab-8B
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

5'-Adenylic acid, monoanhydride with imidodiphosphoric acid. An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It is a potent competitive inhibitor of soluble and membrane-bound mitochondri…

Target Protein:
Glycogen synthase kinase-3 betaThymidylate kinaseChemotaxis protein CheA +46
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Phosphocreatine DB13191
small molecule | CAS: 67-07-2

Phosphocreatine - or creatine phosphate - is the phosphorylated form of creatine. It is primarily found endogenously in the skeletal muscles of vertebrates where it serves a critical role as a rapidly acting energy buffer for muscle cell actions like contract…

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsCardiac Therapy +6
Target Protein:
Guanidinoacetate N-methyltransferaseSodium- and chloride-dependent creatine transporter 1Creatine kinase M-type +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 5746-40-7

Deskripsi belum tersedia.

Kategori:
AminesCompounds used in a research, industrial, or household settingEthylamines +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 51528-59-7

Deskripsi belum tersedia.

Target Protein:
D-tagatose-1,6-bisphosphate aldolase subunit KbaYFructose-bisphosphate aldolase class 2Triosephosphate isomerase +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Soluble calcium-activated nucleotidase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Cell division protein FtsZ
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Phospholipase A2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 4408-78-0

A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent. [PubChem]

Kategori:
AcetatesAcids, AcyclicAnti-Infective Agents +5
Target Protein:
Alkaline phosphatase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Beta-enolase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

The phosphoric acid ester of threonine. Used as an identifier in the analysis of peptides, proteins, and enzymes. [PubChem]

Target Protein:
Aurora kinase ACyclin-dependent kinase 7Protein kinase C theta type +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 21820-51-9

An amino acid that occurs in endogenous proteins. Tyrosine phosphorylation and dephosphorylation plays a role in cellular signal transduction and possibly in cell growth control and carcinogenesis. [PubChem]

Target Protein:
Proto-oncogene tyrosine-protein kinase SrcMast/stem cell growth factor receptor KitTyrosine-protein kinase HCK
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 5875-50-3

Deskripsi belum tersedia.

Kategori:
AlanineAmino AcidsAmino Acids, Peptides, and Proteins +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Phosphoric acid Approved DB09394
small molecule | CAS: 7664-38-2

Phosphoric Acid is a colorless, odorless phosphorus-containing inorganic acid. Phosphoric acid is a sequestering agent which binds many divalent cations, including Fe++, Cu++, Ca++, and Mg++.

Kategori:
Acid Etching, DentalAcidsAcids, Noncarboxylic +5
Waktu ParuhIn infants with nor…
Vol. DistribusiAbsorbed phosphoric…
KlirensAbsorbed phosphate …
Genetik -
small molecule | CAS: 1071-23-4

Deskripsi belum tersedia.

Kategori:
AlcoholsAminesAmino Alcohols
Target Protein:
Protein kinase C beta type
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Phthalic Acid DB02746
small molecule | CAS: 88-99-3

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicOrganic Anion Transporting Polypeptide 2B1 Inhibitors
Target Protein:
Estrogen receptorProgesterone receptorEstrogen receptor beta +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Phthalocyanine DB12983
small molecule | CAS: 574-93-6

Phthalocyanine is under investigation in clinical trial NCT00103246 (Photodynamic Therapy Using Silicon Phthalocyanine 4 in Treating Patients With Actinic Keratosis, Bowen's Disease, Skin Cancer, or Stage I or Stage II Mycosis Fungoides).

Kategori:
Heterocyclic Compounds, Fused-RingPigments, BiologicalRadiation-Sensitizing Agents
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Phylloquinone Approved DB01022
small molecule | CAS: 84-80-0

Vitamin K1, also called phylloquinone or phytonadione, is a fat soluble vitamin.[L33319,L33345] Phylloquinone is a cofactor of the enzyme ?-carboxylase, which modifies and activates precursors to coagulation factors II, VII, IX, and X.[A234264,A234195,A234259…

Kategori:
Blood and Blood Forming OrgansCoagulantsDiet, Food, and Nutrition +20
Target Protein:
Vitamin K-dependent gamma-carboxylaseOsteocalcin
Waktu ParuhIntravenous phylloq…
Vol. DistribusiThe steady state vo…
KlirensIntravenous phylloq…
Genetik -
Physostigmine Approved DB00981
small molecule | CAS: 57-47-6

A cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. It also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticho…

Kategori:
Acids, AcyclicAlkaloidsAntidotes +18
Target Protein:
AcetylcholinesteraseNeuronal acetylcholine receptor subunit alpha-4Neuronal acetylcholine receptor subunit beta-2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Phytic acid DB14981
small molecule | CAS: 83-86-3

Phytic acid is under investigation in clinical trial NCT01000233 (Value of Oral Phytate (InsP6) in the Prevention of Progression of the Cardiovascular Calcifications).

Kategori:
AlcoholsCarbohydratesInositol Phosphates +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Phytochlorin DB19265
small molecule | CAS: 19660-77-6

Phytochlorin is under investigation in clinical trial NCT06311890 (Study to Evaluate the Efficacy, Safety and Tolerability of Photodynamic Therapy(pdt) With Chlorin-e6 in Treating Moderate to Severe Acne).

Kategori:
ChlorophyllHeterocyclic Compounds, Fused-RingRadiation-Sensitizing Agents
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
PI-0824 DB05516
biotech | CAS: 864272-70-8

Pemphigus vulgaris (PV) is an autoimmune disease affecting approximately 40,000 people worldwide. People with PV produce antibodies that attack the cells of the skin, resulting in blisters which, if left untreated, can lead to devastating infections and disco…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
PI-166 DB05859
small molecule

PI-166 is a small organic compound with specific avidity to liver cancer cells. It has demonstrated the ability to reduce the growth of rat hepatomas, which is like human hepatomas, are resistant to established anti-cancer agents.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Pibrentasvir Approved DB13878
small molecule | CAS: 1353900-92-1

Pibrentasvir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS5A inhibitor that targets the the viral RNA replication and viron assembly. In combination with [DB13879], pibrentastiv is a useful therapy for patients who experienced therapeutic …

Kategori:
Antiinfectives for Systemic UseAntiviral AgentsAntivirals for Systemic Use +17
Target Protein:
Nonstructural protein 5A
Waktu ParuhThe elimination hal…
Vol. Distribusi-
Klirens-
Genetik -
Picibanil DB17591
small molecule | CAS: 39325-01-4

Deskripsi belum tersedia.

Kategori:
Antineoplastic AgentsBiological ProductsComplex Mixtures
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Piclamilast DB01791
small molecule | CAS: 144035-83-6

Piclamilast (RP-73,401), is a selective PDE4 inhibitor comparable to other PDE4 inhibitors for its anti-inflammatory effects. It has been investigated for its applications to the treatment of conditions such as chronic obstructive pulmonary disease, bronchopu…

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +4
Target Protein:
3',5'-cyclic-AMP phosphodiesterase 4A3',5'-cyclic-AMP phosphodiesterase 4D3',5'-cyclic-AMP phosphodiesterase 4B +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Picolinic acid DB05483
small molecule | CAS: 98-98-6

PCL-016 or Picolinic acid drug substance is a pyridine carboxylate metabolite of tryptophan. It acts as an anti-infective and immunomodulator and is produced in approximately 25-50 mg quantities by the body on a daily basis through the breakdown of tryptopha…

Kategori:
Chelating AgentsCompounds used in a research, industrial, or household settingIron Chelating Agents +2
Target Protein:
E3 ubiquitin-protein ligase UBR4Zinc finger Y-chromosomal protein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Picosulfuric acid Approved DB09268
small molecule | CAS: 10040-34-3

Picosulfuric acid is found in laxative products. Sodium picosulfate is a used to treat constipation or induce colon cleansing to prepare the large bowels before colonoscopy or surgery. The combination product containing sodium picosulfate and magnesium citrat…

Kategori:
Acids, AcyclicAlimentary Tract and MetabolismContact Laxatives +6
Waktu ParuhThe terminal half-l…
Vol. DistribusiNot available.
KlirensNot available.
Genetik -
Picric acid DB03651
small molecule | CAS: 88-89-1

Used as antiseptic, astringent, and stimulant for epitheliazation.

Kategori:
Benzene DerivativesCompounds used in a research, industrial, or household settingEnzyme Inhibitors +6
Target Protein:
Pentaerythritol tetranitrate reductase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 5001–5050 dari 6694
Sebelumnya Halaman 101 / 134 Berikutnya