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small molecule | CAS: 67308-98-9

Deskripsi belum tersedia.

Kategori:
Testosterone and derivatives
Waktu Paruh-
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Genetik -
1-Testosterone DB01481
small molecule | CAS: 65-06-5

1-Testosterone is an anabolic steroid that differs from testosterone by having a 1,2-double bond instead of 4,5-double bond in its A ring.

Kategori:
AndrostanesAndrostenesAndrostenols +8
Target Protein:
Androgen receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 2747-16-2

17alpha-methyl-4-hydroxynandrolone is a schedule 3 anabolic steroid.

Waktu Paruh-
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Genetik -
small molecule | CAS: 793-55-5

Deskripsi belum tersedia.

Kategori:
Testosterone and derivatives
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 19289-77-1

19-Nor-5-andorstenedione is a prohormone which has the potential to affect bodily levels of testosterone once metabolized in vivo. It is regulated in the United States as a schedule III controlled substance, and prohibited by the World Anti-Doping Agency for …

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small molecule | CAS: 734-32-7

19-Norandrostenedione refers to two steroid isomers that were once marketed as dietary supplements and mainly used by body builders. After 2005, 19-Norandrostenedione was regulated in the United States as a schedule III controlled substance, as well as banned…

Kategori:
17-KetosteroidsAdrenal Cortex HormonesAndrostanes +9
Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule | CAS: 2141-17-5

4-Hydroxytestosterone is testosterone substituted with a hydroxy group on the fourth carbon atom. It is an anabolic steroid with no therapeutic indications, which is prohibited from use in sports by the World Anti-Doping Agency. Formestane (Lentaron) acts …

Kategori:
AndrostanesAndrostenesAndrostenols +4
Waktu Paruh-
Vol. Distribusi-
KlirensClearance is via th…
Genetik -
small molecule | CAS: 571-36-8

5-androstenedione is a prohormone of testosterone. In the United States, the Controlled Substance Act is inclusive to anabolic steroids and their precursors. Thus 5-androstenedione is a controlled substance, and its use in athletes is prohibited by The World …

Kategori:
17-KetosteroidsAdrenal Cortex HormonesAndrostanes +12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 5856-11-1

5alpha-androstane-3beta,17alpha-diol is the unspecified form of the steroid, normally a major metabolite of [testosterone] with androgenic activity. It has been implicated as a regulator of gonadotropin secretion.

Kategori:
Anabolic AgentsAndrostanesAndrostanols +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 571-22-2

Deskripsi belum tersedia.

Kategori:
Testosterone and derivatives
Target Protein:
Aldo-keto reductase family 1 member D1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 53-42-9

The 5-beta-reduced isomer of androsterone. Etiocholanolone is a major metabolite of testosterone and androstenedione in many mammalian species including humans. It is excreted in the urine. [PubChem]

Target Protein:
Immunoglobulin heavy constant gamma 2Sulfotransferase 2A13-alpha-(or 20-beta)-hydroxysteroid dehydrogenase +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Allylestrenol DB01431
small molecule | CAS: 432-60-0

A synthetic steroid with progestational activity. It is widely marketed throughout Europe, including Russia and many other European countries, and is also available in Japan, Hong Kong, India, Bangladesh, Indonesia, and much of Southeast Asia, though notably …

Kategori:
Adrenal Cortex HormonesCytochrome P-450 CYP3A SubstratesCytochrome P-450 CYP3A4 Substrates +13
Target Protein:
Progesterone receptorSodium- and chloride-dependent glycine transporter 1Estrogen receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Androstenediol DB01524
small molecule | CAS: 521-17-5

Androstenediol is an intermediate in [testosterone] biosynthesis, found in the testis or the adrenal glands. Androstenediol, derived from dehydroepiandrosterone by the reduction of the 17-keto group (17-hydroxysteroid dehydrogenases), is converted to testoste…

Kategori:
Anabolic AgentsAndrostanesAndrostenediols +9
Target Protein:
Estrogen receptorEstrogen receptor beta
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Androstenedione DB01536
small molecule | CAS: 63-05-8

A delta-4 C19 steroid that is produced not only in the testis, but also in the ovary and the adrenal cortex. Depending on the tissue type, androstenedione can serve as a precursor to testosterone as well as estrone and estradiol.

Kategori:
17-KetosteroidsAdrenal Cortex HormonesAndrostanes +12
Target Protein:
Aromatase17-beta-hydroxysteroid dehydrogenase type 13 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Boldenone DB01541
small molecule | CAS: 846-48-0

Boldenone is an anabolic steroid developed for veterinary use, mostly for treatment of horses. It is not indicated for use in humans in the US and is only available through veterinary clinics.

Kategori:
Anabolic AgentsAndrostanesAndrostenes +9
Target Protein:
Androgen receptor
Waktu Paruh14 days
Vol. Distribusi-
Klirens-
Genetik -
Calusterone DB01564
small molecule | CAS: 17021-26-0

A 17-alkylated orally active androgenic steroid. A Schedule IV drug in Canada.

Kategori:
AndrostanesAndrostenesAndrostenols +4
Target Protein:
Androgen receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 855-19-6

Deskripsi belum tersedia.

Kategori:
AndrostanesAndrostenesAndrostenols +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Degarelix Approved DB06699
small molecule | CAS: 214766-78-6

Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. This antagonism reduces l…

Kategori:
Amino Acids, Peptides, and ProteinsAntineoplastic AgentsAntineoplastic and Immunomodulating Agents +9
Target Protein:
Gonadotropin-releasing hormone receptor
Waktu ParuhTerminal half-life:…
Vol. DistribusiCentral compartment…
KlirensFollowing subcutane…
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
Testosterone and derivatives
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Desogestrel Approved DB00304
small molecule | CAS: 54024-22-5

Desogestrel, a prodrug, is a third generation progestogen[A176315] and hence, a member of the gonane family which was largely used in Europe before being approved in the US and Canada.[A176339] It was firstly generated from a study that showed that 11-beta an…

Kategori:
Adrenal Cortex HormonesCombination Contraceptives (with Estrogen and derivatives)Contraceptive Agents, Female +25
Target Protein:
Progesterone receptorEstrogen receptor
Waktu ParuhThe terminal half-l…
Vol. DistribusiThe apparent volume…
KlirensThe metabolic clear…
Genetik -
Dienogest Approved DB09123
small molecule | CAS: 65928-58-7

Dienogest is an orally-active semisynthetic progestogen which also possesses the properties of 17?-hydroxyprogesterone. It is a derivative of 19-nortestosterone and has antiandrogenic properties. It is primarily used as a contraceptive in combination with eth…

Kategori:
Adrenal Cortex HormonesAntineoplastic AgentsAntineoplastic Agents, Hormonal +29
Target Protein:
Progesterone receptorAndrogen receptor
Waktu ParuhElimination half-li…
Vol. DistribusiThe apparent volume…
KlirensThe metabolic clear…
Genetik -
Drostanolone DB00858
small molecule | CAS: 58-19-5

Drostanolone (also known as dromostanolone) is a potent synthetic androgenic anabolic steroid similar to testosterone. Drostanolone is indicated in postmenopausal women with recurrent breast cancer, in a combined hormone therapy.

Kategori:
AndrostanesFused-Ring CompoundsSteroids
Target Protein:
Androgen receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Drostanolone propionate Approved DB14655
small molecule | CAS: 521-12-0

Deskripsi belum tersedia.

Kategori:
AndrostanesFused-Ring CompoundsSteroids +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Dutasteride Approved DB01126
small molecule | CAS: 164656-23-9

Dutasteride is an oral synthetic 4-azasteroid commonly marketed under the trade name Avodart. It is a novel dual 5?-reductase inhibitor that works by blocking both isoforms of 5?-reductase enzymes in a potent, selective, and irreversible manner.[A1909] Type I…

Kategori:
5-alpha Reductase InhibitorsAdrenergic alpha-AntagonistsAdrenergic Antagonists +14
Target Protein:
3-oxo-5-alpha-steroid 4-dehydrogenase 1Polyprenal reductase3-oxo-5-alpha-steroid 4-dehydrogenase 2
Waktu ParuhThe terminal elimin…
Vol. DistribusiDutasteride display…
KlirensIn a study of healt…
Genetik -
Epitestosterone DB07768
small molecule | CAS: 481-30-1

Epitestosterone is the 17-alpha isomer of testosterone, derived from pregnenolone via the delta5-steroid pathway, and via 5-androstene-3-beta,17-alpha-diol. Epitestosterone acts as an antiandrogen in various target tissues. The ratio between testosterone/epit…

Kategori:
AndrostanesAndrostenesAndrostenols +7
Target Protein:
Aldo-keto reductase family 1 member C1Aldo-keto reductase family 1 member C2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Estrone Approved DB00655
small molecule | CAS: 53-16-7

Estrone, one of the major mammalian estrogens, is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone. It is produced in vivo from androstenedione or from testosterone via estradiol. It is produced primarily in the ovaries, placenta, and in peri…

Kategori:
17-KetosteroidsAdrenal Cortex HormonesBCRP/ABCG2 Inhibitors +28
Target Protein:
Estrogen receptorEstrogen receptor betaAndrogen receptor +2
Waktu Paruh19 hours
Vol. Distribusi-
Klirens-
Genetik -
Etonogestrel Approved DB00294
small molecule | CAS: 54048-10-1

Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel.[A37184] The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in…

Kategori:
Adrenal Cortex HormonesCombination Contraceptives (with Estrogen and derivatives)Contraceptive Agents, Female +18
Target Protein:
Progesterone receptor
Waktu ParuhThe elimination hal…
Vol. DistribusiThe apparent volume…
KlirensThe clearance rate …
Genetik -
Finasteride Approved DB01216
small molecule | CAS: 98319-26-7

Finasteride is a synthetic 4-azasteroid compound [L10565] and specific inhibitor of steroid Type II 5?-reductase, which is an intracellular enzyme that converts the androgen testosterone into 5?-dihydrotestosterone (DHT). It works in a similar fashion as [dut…

Kategori:
5-alpha Reductase InhibitorsAdrenergic alpha-AntagonistsAdrenergic Antagonists +22
Target Protein:
3-oxo-5-alpha-steroid 4-dehydrogenase 2Polyprenal reductase3-oxo-5-alpha-steroid 4-dehydrogenase 1 +1
Waktu ParuhIn healthy young su…
Vol. DistribusiThe volume of distr…
KlirensIn healthy young su…
Genetik -
Fluoxymesterone Approved DB01185
small molecule | CAS: 76-43-7

An anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and in the treatment of breast neoplasms in women.

Kategori:
3-Oxoandrosten (4) DerivativesAnabolic AgentsAndrogens +11
Target Protein:
Androgen receptorEstrogen receptorGlucocorticoid receptor +1
Waktu Paruh9.2 hours
Vol. Distribusi-
Klirens-
Genetik -
Formebolone DB01569
small molecule | CAS: 2454-11-7

Formebolone, a derivative of androstane, is an anabolic androgenic steroid. It is on the list of substances prohibited by the Word Anti-Doping Agency, and is regularly screened for in athletes.[A14416] It is also classified by the US Drug Enforcement Administ…

Kategori:
AndrostanesAndrostenesAndrostenols +3
Target Protein:
11-beta-hydroxysteroid dehydrogenase type 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Formestane Approved DB08905
small molecule | CAS: 566-48-3

Formestane was the first selective, type I, steroidal aromatase inhibitor used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women. Formestane suppresses estrogen production from anabolic steroids or prohormones. Formestane i…

Kategori:
17-KetosteroidsAdrenal Cortex HormonesAndrostanes +23
Target Protein:
Aromatase
Waktu ParuhTerminal plasma eli…
Vol. DistribusiVd = 1.8 L/kg; wide…
KlirensPlasma clearance is…
Genetik -
Gestrinone Approved DB11619
small molecule | CAS: 16320-04-0

Gestrinone, also known as ethylnorgestrienone, is a synthetic steroid of the 19-nortestosterone group that is marketed in Europe, Australia, and Latin America, though not the United States or Canada, and is used primarily in the treatment of endometriosis. …

Kategori:
Adrenal Cortex HormonesAntigonadotropins and Similar AgentsContraceptive Agents, Female +19
Target Protein:
Progesterone receptorGlucocorticoid receptorAndrogen receptor +3
Waktu ParuhPlasma half-life is…
Vol. Distribusi67 L [L1700]
KlirensRenal Excretion acc…
Genetik -
Ginsenoside Rb1 DB06749
small molecule | CAS: 41753-43-9

Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng). Ginsenosides have been the target of research, as they are viewed as the active compounds behind the claims of ginseng's efficacy. B…

Kategori:
CarbohydratesGlycosidesOATP1B3 inhibitors +4
Target Protein:
Solute carrier organic anion transporter family member 1B3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Goserelin Approved DB00014
small molecule | CAS: 65807-02-5

Goserelin is a synthetic hormone. In men, it stops the production of the hormone testosterone, which may stimulate the growth of cancer cells. In women, goserelin decreases the production of the hormone estradiol (which may stimulate the growth of cancer cell…

Kategori:
Adrenal Cortex HormonesAmino Acids, Peptides, and ProteinsAntineoplastic Agents +22
Target Protein:
Lutropin-choriogonadotropic hormone receptorProgonadoliberin-1Gonadotropin-releasing hormone receptor
Waktu Paruh4-5 hours
Vol. Distribusi* 44.1 ± 13.6 L [su…
Klirens* 121 +/- 42.4 mL/m…
Genetik -
Histrelin Approved DB06788
small molecule | CAS: 76712-82-8

Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin when administered as an implant delivering continuous therapeutic doses. This drug is a synthetic analog of naturally occurring GnRH with a higher pot…

Kategori:
Adrenal Cortex HormonesAmino Acids, Peptides, and ProteinsAntineoplastic and Immunomodulating Agents +17
Target Protein:
Gonadotropin-releasing hormone receptor
Waktu ParuhIn healthy voluntee…
Vol. DistribusiThe apparent volume…
KlirensIn prostate cancer …
Genetik -
Levonorgestrel Approved DB00367
small molecule | CAS: 797-63-7

Levonorgestrel (LNG) is a synthetic progestogen similar to [Progesterone] used in contraception and hormone therapy.[A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an …

Kategori:
Adrenal Cortex HormonesCombination Contraceptives (with Estrogen and derivatives)Contraceptive Agents, Female +23
Target Protein:
Progesterone receptor3-oxo-5-alpha-steroid 4-dehydrogenase 1Estrogen receptor +3
Waktu ParuhThe elimination hal…
Vol. DistribusiOne pharmacokinetic…
KlirensClearance was found…
Genetik -
Lutropin alfa Approved DB00044
biotech | CAS: 152923-57-4

Lutropin alfa is a recombinant human luteinizing hormone produced in yeast with 2 subunits, alpha = 92 residues, beta = 121 residues. It is a heterodimeric glycoprotein made up of monomeric units. Lutropin alfa was the first and only recombinant human form of…

Kategori:
Genito Urinary System and Sex HormonesGonadotropinsGonadotropins and Antigonadotropins +1
Target Protein:
Lutropin-choriogonadotropic hormone receptor
Waktu ParuhBiphasic; terminal …
Vol. DistribusiThe steady state vo…
Klirens* 2 – 3 L/h [health…
Genetik -
Mesterolone DB13587
small molecule | CAS: 1424-00-6

Mesterolone is a synthetic anabolic-androgenic steroid (AAS) and derivative of dihydrotestosterone (DHT). It is inactivated by 3?-hydroxysteroid dehydrogenase in skeleta muscules so it is considered a weak androgen. It is not a substrate for aromatase so it i…

Kategori:
5-Androstanon (3) DerivativesAnabolic AgentsAndrogens +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 65-04-3

Methyl-1-testosterone is a synthetic and orally active anabolic–androgenic steroid (AAS) which was never marketed for medical use. It is a derivative of 1-testosterone with a methyl group in the carbon 17. Methyl-1-testosterone is considered a prohibited dopi…

Kategori:
Testosterone and derivatives
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Methyltestosterone Approved DB06710
small molecule | CAS: 58-18-4

A synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement therapies. Also, has antineoplastic properties and so has been used secondarily in women with advanced breast cancer. Methyltestosterone is a sched…

Kategori:
3-Oxoandrosten (4) DerivativesAnabolic AgentsAndrogens +20
Target Protein:
Androgen receptorEstrogen receptor
Waktu Paruh6-8 hours
Vol. Distribusi-
Klirens-
Genetik -
Mibolerone DB11429
small molecule | CAS: 3704-09-4

Mibolerone is a potent anabolic steroid which is both higher affinity and more selective for the androgen receptor than metribolone.

Kategori:
EstranesEstrenesFused-Ring Compounds +7
Target Protein:
Androgen receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Nandrolone DB13169
small molecule | CAS: 434-22-0

Nandrolone, also known as 19-nortestosterone or 19-norandrostenolone, is a synthetic anabolic-androgenic steroid (AAS) derived from testosterone.

Kategori:
Alimentary Tract and MetabolismAnabolic AgentsAnabolic Agents for Systemic Use +16
Target Protein:
Androgen receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Nandrolone decanoate Approved DB08804
small molecule | CAS: 360-70-3

Nandrolone decanoate, also known as nandrolone caprinate, is an alkylated anabolic steroid indicated in the management of anemia of renal insufficiency and as an adjunct therapy in the treatment of senile and postmenopausal osteoporosis.[A233789,A233849,L3256…

Kategori:
Anabolic AgentsAndrogensBone Density Conservation Agents +16
Target Protein:
Androgen receptorProtein c-Fos5-hydroxytryptamine 2 receptor +3
Waktu ParuhNandrolone decanoat…
Vol. Distribusi-
Klirens50 mg, 100 mg, and …
Genetik -
Nandrolone phenpropionate Approved DB00984
small molecule | CAS: 62-90-8

C18 steroid with androgenic and anabolic properties. It is generally prepared from alkyl ethers of estradiol to resemble testosterone but less one carbon at the 19 position. It is a schedule III drug in the U.S.

Kategori:
Anabolic AgentsAndrogensEstranes +10
Target Protein:
Androgen receptor
Waktu ParuhThe elimination hal…
Vol. Distribusi-
Klirens-
Genetik -
Norethisterone Approved DB00717
small molecule | CAS: 68-22-4

Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins.[A10367] It is further classified as a second-generation progestin, along with [levonorgestrel] and its derivati…

Kategori:
Adrenal Cortex HormonesAnti-Gonadotropin-Releasing HormonesCombination Contraceptives (with Estrogen and derivatives) +34
Target Protein:
Progesterone receptorAndrogen receptorGlucocorticoid receptor
Waktu ParuhThe half-life of no…
Vol. DistribusiThe volume of distr…
KlirensThe plasma clearanc…
Genetik -
Oxabolone DB01500
small molecule | CAS: 4721-69-1

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 1254-35-9

Oxabolone cipionate is the C17? cypionate ester and a prodrug of [DB01500]. A synthetic anabolic-androgenic (AAS) steroid, it is a derivative of 19-nortestosterone (nandrolone). It is considered as a performance enhancing drug thus is prohibited from use in s…

Kategori:
Alimentary Tract and MetabolismAnabolic Agents for Systemic UseAnabolic Steroids +11
Waktu Paruh-
Vol. Distribusi-
KlirensThe elimination on …
Genetik -
Prasterone Approved DB01708
small molecule | CAS: 53-43-0

Prasterone, also known as dehydroepiandrosterone (DHEA) is a major C19 steroid produced by the adrenal cortex. It is also produced in small quantities in the testis and the ovary. Dehydroepiandrosterone (DHEA) can be converted to testosterone; androstenedione…

Kategori:
17-KetosteroidsAdjuvants, ImmunologicAdrenal Cortex Hormones +32
Target Protein:
Glucose-6-phosphate 1-dehydrogenaseEstrogen receptorEstrogen receptor beta +7
Waktu Paruh12 hours
Vol. Distribusi-
Klirens-
Genetik -
Relugolix Approved DB11853
small molecule | CAS: 737789-87-6

Relugolix is a gonadotropin-releasing hormone (GnRH) receptor antagonist used in the treatment of several hormone-responsive conditions. It was first approved in Japan in 2019, under the brand name Relumina, for the symptomatic treatment of uterine fibroids,[…

Kategori:
AmidesAnti-Gonadotropin-Releasing HormonesAntiandrogens +30
Target Protein:
Gonadotropin-releasing hormone receptor
Waktu ParuhThe average effecti…
Vol. Distribusi-
KlirensThe average renal c…
Genetik -
Stanolone DB02901
small molecule | CAS: 521-18-6

A potent androgenic metabolite of testosterone. Dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone. Unlike testosterone, DHT cannot be aromatized to estradiol therefore DHT is considered a pure androgenic steroid.

Kategori:
5-Androstanon (3) DerivativesAlimentary Tract and MetabolismAnabolic Agents for Systemic Use +17
Target Protein:
Androgen receptorEstrogen receptorMineralocorticoid receptor +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
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