Digital Pharmacy - Dashboard Peneliti

(1R,2S)-2-(5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)cyclohexanecarboxylic acid DB07850

small molecule

Deskripsi belum tersedia.

Target Protein:

Beta-lactamase

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(1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE DB07072

small molecule

Deskripsi belum tersedia.

Target Protein:

Dipeptidyl peptidase 4

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(2R)-4-[(8R)-8-METHYL-2-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[1,5-A]PYRAZIN-7(8H)-YL]-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE DB07081

small molecule

Deskripsi belum tersedia.

Target Protein:

Dipeptidyl peptidase 4

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(2S,3S)-3-AMINO-4-(3,3-DIFLUOROPYRROLIDIN-1-YL)-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-6-YLCYCLOHEXYL)BUTANAMIDE DB07092

small molecule

Deskripsi belum tersedia.

Target Protein:

Dipeptidyl peptidase 4

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(2S,3S)-3-AMINO-4-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-5-YLCYCLOHEXYL)BUTANAMIDE DB07135

small molecule

Deskripsi belum tersedia.

Target Protein:

Dipeptidyl peptidase 4

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(2S,3S)-3-{3-[2-chloro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-cyclopentylidene-4-cyclopropyl-1-fluorobutan-2-amine DB06994

small molecule

Deskripsi belum tersedia.

Target Protein:

Dipeptidyl peptidase 4

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(2S,3S)-3-{3-[4-(METHYLSULFONYL)PHENYL]-1,2,4-OXADIAZOL-5-YL}-1-OXO-1-PYRROLIDIN-1-YLBUTAN-2-AMINE DB07067

small molecule

Deskripsi belum tersedia.

Target Protein:

Dipeptidyl peptidase 4

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(2S,3S)-4-cyclopropyl-3-{(3R,5R)-3-[2-fluoro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazolidin-5-yl}-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxobutan-2-amine DB06993

small molecule

Deskripsi belum tersedia.

Target Protein:

Dipeptidyl peptidase 4

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(3S)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide DB08303

small molecule

Deskripsi belum tersedia.

Target Protein:

Glutamate receptor 2

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(4R)-7,8-dichloro-1',9-dimethyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile DB07242

small molecule

Deskripsi belum tersedia.

Target Protein:

Death-associated protein kinase 3Serine/threonine-protein kinase pim-1

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(4R)-7-chloro-9-methyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile DB08166

small molecule

Deskripsi belum tersedia.

Target Protein:

Serine/threonine-protein kinase pim-1

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1,2,4-Triazole DB03594

small molecule | CAS: 63598-71-0

Deskripsi belum tersedia.

Target Protein:

Carbonic anhydrase 2

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1,2,4-Triazole-Carboxamidine DB02048

small molecule

Deskripsi belum tersedia.

Target Protein:

Nitric oxide synthase 3

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1-(2-cyclopropylethyl)-3-(1,1-dioxo-2H-1,2,4-benzothiadiazin-3-yl)-6-fluoro-4-hydroxy-2(1H)-quinolinone DB08278

small molecule | CAS: 477931-14-9

Deskripsi belum tersedia.

Kategori:

Heterocyclic Compounds, Fused-RingQuinolinesRNA Replicase, antagonists & inhibitors +3

Target Protein:

Genome polyprotein

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1-(3,5-DICHLOROPHENYL)-5-METHYL-1H-1,2,4-TRIAZOLE-3-CARBOXYLIC ACID DB07852

small molecule

Deskripsi belum tersedia.

Target Protein:

Cyclin-A2Cyclin-dependent kinase 2

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1-(thiophen-2-ylacetyl)-4-(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)piperidine DB08471

small molecule

Deskripsi belum tersedia.

Target Protein:

HTH-type transcriptional regulator EthR

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1-[5-Methyl-2-(trifluoromethyl)furan-3-yl]-3-[5-[2-[[6-(1H-1,2,4-triazol-5-ylamino)pyrimidin-4-yl]amino]ethyl]-1,3-thiazol-2-yl]urea DB07789

small molecule

Deskripsi belum tersedia.

Target Protein:

Serine/threonine-protein kinase PLK1

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2-(methylamino)-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide DB08118

small molecule

Deskripsi belum tersedia.

Target Protein:

Hexokinase-4

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2-amino-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide DB07358

small molecule

Deskripsi belum tersedia.

Target Protein:

Hexokinase-4

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2-Methylpentane-1,2,4-Triol DB01881

small molecule

Deskripsi belum tersedia.

Target Protein:

Xylose isomerase

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2-[4-(4-Hydroxy-3-Isopropyl-Phenoxy)-3,5-Dimethyl-Phenyl]-2h-[1,2,4]Triazine-3,5-Dione DB03181

small molecule

Deskripsi belum tersedia.

Target Protein:

Thyroid hormone receptor beta

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3-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)quinolin-2(1H)-one DB07275

small molecule

Deskripsi belum tersedia.

Target Protein:

Genome polyprotein

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3-(4-CHLOROPHENYL)-5-(METHYLTHIO)-4H-1,2,4-TRIAZOLE DB08062

small molecule

Deskripsi belum tersedia.

Target Protein:

Prothrombin

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3-(4-fluorophenyl)-5-phenyl-4H-1,2,4-triazole DB08470

small molecule

Deskripsi belum tersedia.

Target Protein:

HTH-type transcriptional regulator EthR

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3-[(4-fluorophenyl)sulfanyl]-N-(4-methyl-1,3-thiazol-2-yl)-6-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]pyridine-2-carboxamide DB07359

small molecule

Deskripsi belum tersedia.

Target Protein:

Hexokinase-4

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3-{[(5R,6R)-5-Benzyl-6-hydroxy-2,4-bis(4-hydroxybenzyl)-3-oxo-1,2,4-triazepan-1-yl]sulfonyl}benzonitril DB03141

small molecule

Deskripsi belum tersedia.

Target Protein:

Gag-Pol polyproteinV-1 protease

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4-(2-(3-Propyl-(1,2,4)oxadiazol-5-yl)-vinyl)-benzene-1,2-diol DB17138

small molecule | CAS: 1332498-21-1

Deskripsi belum tersedia.

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4-({5-[(4-AMINOCYCLOHEXYL)AMINO][1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL}AMINO)BENZENESULFONAMIDE DB07687

small molecule

Deskripsi belum tersedia.

Target Protein:

Cyclin-dependent kinase 2

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4-AMINO-5-(2-METHYLPHENYL)-2,4-DIHYDRO-3H-1,2,4-TRIAZOLE-3-THIONE DB08069

small molecule

Deskripsi belum tersedia.

Target Protein:

Metallo-beta-lactamase L1

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4-[(3-BROMO-4-O-SULFAMOYLBENZYL)(4-CYANOPHENYL)AMINO]-4H-[1,2,4]-TRIAZOLE DB04600

small molecule

Deskripsi belum tersedia.

Target Protein:

Carbonic anhydrase 2

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4-[(4-O-SULFAMOYLBENZYL)(4-CYANOPHENYL)AMINO]-4H-[1,2,4]-TRIAZOLE DB04601

small molecule

Deskripsi belum tersedia.

Target Protein:

Carbonic anhydrase 2

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4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]phenol DB08111

small molecule

Deskripsi belum tersedia.

Target Protein:

Met proto-oncogene variant

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4-[3-(3-NITROPHENYL)-1,2,4-OXADIAZOL-5-YL]BUTANOIC ACID DB07498

small molecule

Deskripsi belum tersedia.

Target Protein:

Aldo-keto reductase family 1 member B1

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4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol DB08770

small molecule

Deskripsi belum tersedia.

Target Protein:

Adenosine receptor A1Adenosine receptor A2bAdenosine receptor A2a

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4-{[5-(CYCLOHEXYLAMINO)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE DB07686

small molecule

Deskripsi belum tersedia.

Target Protein:

Cyclin-dependent kinase 2

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4-{[5-(CYCLOHEXYLMETHOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE DB07685

small molecule

Deskripsi belum tersedia.

Target Protein:

Cyclin-dependent kinase 2

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4-{[5-(CYCLOHEXYLOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE DB07688

small molecule

Deskripsi belum tersedia.

Target Protein:

Cyclin-dependent kinase 2Cyclin-A2

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5-(4-((2S,5S)-5-(4-chlorobenzyl)-2-methylmorpholino)piperidin-1-yl)-1H-1,2,4-triazol-3-amine DB18065

small molecule | CAS: 2088453-21-6

Deskripsi belum tersedia.

Kategori:

Enzyme InhibitorsProtein Kinase Inhibitors

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5-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1H-1,2,4-TRIAZOLE-3-SULFONAMIDE DB07804

small molecule

Deskripsi belum tersedia.

Target Protein:

Coagulation factor X

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5-hydroxy-4-(7-methoxy-1,1-dioxido-2H-1,2,4-benzothiadiazin-3-yl)-2-(3-methylbutyl)-6-phenylpyridazin-3(2H)-one DB06974

small molecule

Deskripsi belum tersedia.

Target Protein:

Genome polyprotein

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5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine DB08008

small molecule

Deskripsi belum tersedia.

Target Protein:

Dihydroorotate dehydrogenase (quinone), mitochondrial

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6-(4-{(1S,2S)-2-AMINO-1-[(DIMETHYLAMINO)CARBONYL]-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-3-OXOPROPYL}PHENYL)-1H-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-4-IUM DB08504

small molecule

Deskripsi belum tersedia.

Target Protein:

Dipeptidyl peptidase 4

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6-CHLORO-3-(DICHLOROMETHYL)-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE 1,1-DIOXIDE DB08645

small molecule

Deskripsi belum tersedia.

Target Protein:

Carbonic anhydrase 2

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ABT-341 DB08044

small molecule | CAS: 913623-69-5

ABT-341 is a potent and selective DPP-4 inhibitor with a structure very similar to sitagliptin (in 2D; the 3D structure is significantly different). [A39406]

Kategori:

Benzene DerivativesEnzyme InhibitorsProtease Inhibitors

Target Protein:

Dipeptidyl peptidase 4

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Aficamten DB18490

small molecule | CAS: 2364554-48-1

Deskripsi belum tersedia.

Target Protein:

Myosin-binding protein C, cardiac-type

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AMG-208 DB08079

small molecule | CAS: 1002304-34-8

AMG-208 has been used in trials studying the treatment of Cancer, Tumors, Oncology, Prostate Cancer, and Oncology Patients, among others.

Target Protein:

Hepatocyte growth factor receptor

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Anastrozole Approved DB01217

small molecule | CAS: 120511-73-1

Anastrozole is a non-steroidal aromatase inhibitor (AI), similar to [letrozole], used to decrease circulating estrogen levels in the treatment of postmenopausal women with estrogen-responsive breast cancer.[L8863] Anastrozole is also related to [exemestane], …

Kategori:

Antineoplastic AgentsAntineoplastic Agents, HormonalAntineoplastic and Immunomodulating Agents +30

Target Protein:

Aromatase

Waktu ParuhThe elimination hal…

Vol. DistribusiThe volume of distr…

KlirensAnastrozole's clear…

Genetik -

ANC-501 DB18907

small molecule | CAS: 1370444-22-6

ANC-501 is under investigation in clinical trial NCT05439603 (ANC-501 in the Treatment of Adults With Major Depressive Disorder).

Kategori:

AcetatesAcids, AcyclicAmides +1

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Arterolane DB19027

small molecule | CAS: 664338-39-0

Arterolane is under investigation in clinical trial NCT03452475 (Comparison of Arterolane-piperaquine Versus Arterolane-piperaquine+mefloquine Versus Artemether-lumefantrine in Kenyan Children).

Kategori:

AnionsAntimalarialsAntiparasitic Products, Insecticides and Repellents +7

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Ataluren Approved DB05016

small molecule | CAS: 775304-57-9

Ataluren is a novel, orally administered drug that targets nonsense mutations. Ataluren is approved for use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and older who are able to walk. More specifically, atalu…

Kategori:

Musculo-Skeletal SystemOAT1/SLC22A6 inhibitorsOAT3/SLC22A8 Inhibitors +3

Target Protein:

Dystrophin

Waktu ParuhAtaluren plasma hal…

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